WINNIPEG, MB--(Marketwired - December 07, 2016) - 3D Signatures Inc. (TSX VENTURE: DXD) (the "Company" or "3DS") presented the preliminary results of an important collaborative initiative between the Company and the Institut Universitaire de Cardiologie et de Pneumologie De Quebec (IUCPQ) exploring the possibility of identifying a biological marker to distinguish between two deadly forms of lung cancer, multiple synchronous lung adenocarcinoma (AC) and metastatic lung AC, which is a significant unmet clinical need in the management of patients with multiple lung lesions. In every blinded patient sample the Company analyzed, 3DS technology was able to distinguish between the two respective types of deadly lung cancer. The poster is being presented at the International Association for the Study of Lung Cancer (IASLC) 17th World Conference on Lung Cancer (WCLC) taking place in Vienna, Austria from December 4 to 7, 2016.
3DS technology was used to differentiate blindly between 19 lung cancer patients, 10 with synchronous lung AC and 9 with metastatic AC. Patient tissue samples were provided by the Biobank at IUCPQ and the experimental study design was the result of a fruitful collaboration between Dr. Philippe Joubert, Thoracic Pathologist and Scientist at IUCPQ, Dr. Sabine Mai, co-founder of 3DS and Dr. Oumar Samassekou, VP Clinical Programs at 3DS. The acquisition of 3D telomere images and analysis was performed in the Company's reference lab using 3DS' proprietary software platform, TeloView™, while the experiments, data analysis and interpretation was performed in a multi-centre collaboration between Dr. Sabine Mai, Dr Philippe Joubert and Nathalie Bastien, a postdoctoral fellow at IUCPQ.
Principal Investigator, Dr. Philippe Joubert, and Company Director and Chair of 3DS' Clinical and Scientific Advisory Board, Dr. Sabine Mai stated:
This important research would not be possible without the support of IUCPQ. These preliminary results suggest that 3DS has a promising molecular imaging technology that has the potential to improve the management of AC patients who present with multiple lung lesions.
Currently, there is no molecular tool to aid clinicians in distinguishing between patients with synchronous lung AC and patients with metastatic lung AC. While only patients with synchronous lung cancer are likely to benefit from surgical resection, it is important for the treating physician to accurately identify these two groups of patients in order to optimize their management. 3DS' platform technology has the potential to help clincians personalize treatments for a significant portion of lung cancer patients -- and potentially improve outcomes in one of the most deadly forms of lung cancer. Additional studies are being planned between IUCPQ and 3DS to further validate these results and move 3DS' novel biomarker closer to commercialization.
