by
Gus Iversen, Editor in Chief | October 11, 2017
From the October 2017 issue of HealthCare Business News magazine
The good news is that the researchers didn't detect any histologic changes that suggest toxicity in patients who were exposed to gadolinium.
Exploring alternatives
While the scientific community is in agreement that gadolinium does more good than harm, some researchers are developing an alternative to gadolinium-based contrast agents. In February, a team from the Massachusetts Institute of Technology published findings in the Proceedings of the National Academy of Sciences suggesting that there may be another option in the pipeline.
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The researchers found that similar MR contrast can be produced with small iron oxide nanoparticles that have been treated with a zwitterion coating. Zwitterions are molecules that have areas of positive and negative electrical charges that cancel out and make them neutral.
The new iron oxide nanoparticles, they reported, may be safer for patients with impaired kidney function, for whom gadolinium exposure can increase the risk of nephrogenic systemic fibrosis.
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