DENVER, April 22, 2021 /PRNewswire/ -- CereHealth Corporation, a data analytics technology company that provides Medical Analytics as a Service (MAaaS), was granted a third patent on its novel systems and methodologies used in its FDA-cleared CereMetrix® medical imaging and data analytics software. On May 4, 2021, the United States Patent and Trademark Office will issue the company's patent 10/997,715 for proprietary use of a medical imaging composite average and clustering technique to identify regions of interest within a medical image. The system, method, and medium described in the patent provides unique advantages to medical providers, patients, clinicians, researchers, and other entities in the medical field.
Currently, quantification of biological processes within medical imaging is often contingent on comparing imaging results to a set of normals or controls. In certain instances, the identified control groups are small and true control datasets are difficult to accumulate. In addition, normal variation contained in the human body makes analysis of subtle differences challenging when only performing a qualitative analysis. The now patented, innovative system creates a "composite" dataset combining heterogeneous clinical scans that have been acquired using consistent protocols and processing techniques. Following a comparison between the composite dataset and a patient's scan, clustering may then be applied to the output to identify groups of voxels that meet qualifying criteria.
CereHealth's composite average methodology is foundational in its QSPECT® brain imaging analysis tool, a component of the CereMetrix Ai quantitative imaging and analytics platform, which received FDA 510(k) medical device clearance in February 2018. When applied to qSPECT brain imaging, this technique produced a composite that was noninferior to that of a smaller set of controls. This work was explained in detail in "Going Against the Norm: Validation of a Novel Alternative to Brain SPECT Normative Datasets," co-authored by Lindsay Quandt and Dr. Cyrus Raji and published in Exploration of Medicine, a peer-reviewed, open access online journal known for its substantial and novel insights into medicine.
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"With each innovation we are breaking down the barriers between medicine and technology," said John Kelley, Chairman and CEO of CereHealth Corp., and an inventor on the patent. "We are disrupting the status quo and therefore accelerating medical advancement and precision medicine."