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Oncology Homepage

Is low cost Proton-to-Carbon Heavy Ion radiotherapy coming soon? Best Particle Therapy plans to bring smaller footprint system to market in two to three years

Researchers develop AI approach for high-risk clinical tumor volumes Assisting low- and middle-income countries that lack contouring expertise

Dr. Benjamin Movsas American Radium Society Names president-elect

Tennessee governor vetoes state employee proton therapy coverage Would require PT to be covered under the same aggregate amount as IMRT

European medical center first to perform linac-based MR-guided RT using on-table adaptation Made possible with ViewRay's MRIdian Linac

AI approach used to study Mars now assessing tumor response to therapies Could reduce sample sizes and accelerate process for approval of cancer therapies

Hospital in Italy performs radiosurgery with Brainlab's Elements Spine SRS software Automatically plans treatments for complex parts of the body

Thermal imaging in development could provide real-time ablation views Taking guesswork and additional imaging out of the equation

PPI to purchase Elekta MR-linac systems for £25 million Will install at five cancer centers across the UK

Dr. Nancy P. Mendenhall Medical Director of UF Health Proton Therapy selected by University of Florida as 2018 Clinical Science Researcher of the Year

Results from proof-of-concept
study are in

New algorithm may significantly reduce side effects of radiotherapy

por Lauren Dubinsky , Senior Reporter
A new algorithm developed at North Carolina State University may have the potential to dramatically reduce the side effects of radiation therapy.

"Even after decades of development, the efficacy of radiation therapy treatments is limited by the side effects that arise from unwanted radiation to healthy tissue," Dávid Papp, assistant professor at the university, told HCB News.

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Current clinical protocols have patients receive the same radiation dose for each treatment session, but Papp and his team decided to investigate the effectiveness of administering different doses.

In a proof-of-concept study, the team tested this new protocol, called spatiotemporal fractionation, against model slices of five differential liver tumors — each representing a specific size or location.

They discovered that this new protocol reduced the liver radiation dose by 13 to 35 percent while delivering the same results as conventional radiation therapy.

Papp noted that a 20 percent reduction in side effects is enough to warrant a change in standard clinical practice.

The results were published in Physics in Medicine and Biology. The team is now working on refining the protocol to make it more robust, and they plan to conduct in vivo testing next.

"We can only speculate, but I believe [this protocol] has the potential to change how cancer patients with certain tumor types are treated, and to do so with only minimal investment required from the clinics," said Papp.

He added that one of the most pertinent questions is whether these new types of treatments can be designed and delivered just as easily and safely as conventional treatments. Clinical trials will help answer that.

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