DOTmed Home MRI Oncology Ultrasound Molecular Imaging X-Ray Cardiology Health IT Business Affairs
News Home Parts & Service Operating Room CT Women's Health Proton Therapy Endoscopy HTMs Mobile Imaging
SEARCH
Posição atual:
>
> This Story

starstarstarstarstar (1)
Início de uma sessão ou Registo to rate this News Story
Forward Printable StoryPrint Comment

 

MRI Homepage

Siemens Healthineers collaborates with Houston Methodist Hospital Will provide advanced angio, MR, CT, molecular imaging and ultrasound technology

MR imaging shows significant brain differences in autism patients Researchers gain better understanding of the disorder

Researchers leverage PET and MR to uncover serotonin's role in Alzheimer's Is it the cause or effect?

Shared Imaging provides mobile imaging systems to Kelsey-Seybold Clinic for monthly fee "Functional service" business model

UK and German universities to install MEG systems New brain imaging system records healthy and pathological brain signals

Louisiana hospitals deploy Synaptive's BrightMatter technology Builds on earlier investments in neuroscience

FDA clears Stimwave's peripheral nerve stimulator system for full-body MR exams StimQ is 5 percent the size of competitor systems

'Glaring void' in diagnostics prompts 3-D MR solution for life-threatening births Researchers show 86 percent accuracy in diagnosing the problem

New Chinese vehicle brings MR to remote regions Chiying A30 was developed and produced by XBO Medical Systems

GE Healthcare gets FDA nod for SIGNA Premier MR system Wide bore 3T system is aimed at neurology and oncology

Computational model of the cortical
and subcortical brain structures that
form the basis of the BrainPrint

Can MR detect Alzheimer's before symptoms have even appeared?

por Lauren Dubinsky , Senior Reporter
A team of researchers at Massachusetts General Hospital (MGH) have found a way to spot individuals in the early presymptomatic stages of Alzheimer’s disease with MR. The scans revealed that those with the disease had asymmetrical brain structures in the left and right sides of the brain.

“Compared to the size of a structure, the geometric shape can pick up subtle changes in sub-structures much earlier,” Martin Reuter, lead researcher, told HCB News. “Lateral asymmetries in dementia may have been overlooked for that reason in the past.”

Story Continues Below Advertisement

The (#1 Resource) for Medical Imaging and Peripherals. Call 1-949-273-8000

As a Master Distributor for major brands Barco, Philips, and Sony, we offer custom imaging solutions. With our renowned OEM Solutions and Service/Repair Center, Ampronix is a one-stop shop for HD Medical LCD Displays--Printers--Recorders--4K Cameras



In particular, the asymmetry of the hippocampus and amygdala increases as the disease becomes more severe. The researchers believe the asymmetry of those and a few other structures could be a biomarker for detecting early-stage dementia.

The team developed a computer-aided system called BrainPrint that represents the whole brain based on the shapes, rather than the size or volume, of the structures. An article published in 2015 in the journal, NeuroImage, showed that BrainPrint can be as accurate as a fingerprint in distinguishing individuals.

This new study used BrainPrint to evaluate structural asymmetries in MR images of 700 patients involved in the National Institute of Health-sponsored Alzheimer’s Disease Neuroimaging Initiative (ADNI). The participants received an MR exam at enrollment and then again every six to 12 months, along with cognitive and genetic testing.

The researchers assessed the data from ANDI participants that underwent at least three MR exams. They were then divided into four groups: those diagnosed with probable Alzheimer’s when entering the study, healthy controls with no sign of dementia, those with mild cognitive impairment (MCI) that remained stable over two to three years and those with MCI that progressed to Alzheimer’s.

BrainPrint revealed that differences in the shapes of the hippocampus and amygdala were highest in individuals with dementia and lowest in the healthy controls. Among the group that was diagnosed with MCI, the baseline asymmetry was higher in those that developed Alzheimer’s, and increased even more as symptoms became apparent.

“Clinical Alzheimer’s disease diagnosis occurs very late. By that time decades of advanced neurodegeneration have taken their toll and large portions of the brain are atrophied,” said Reuter. “Recovery at this stage is unlikely, even stopping or significantly slowing the neurodegenerative process at this time will be very difficult.”

If presymptomatic or early-stage individuals at risk of developing the disease are identified, they can be recruited into studies investigating novel therapies, because preventive treatment can still be successful.

Reuter and his team are planning to further explore the relationship between brain asymmetries and established Alzheimer’s disease biomarkers to get a better understanding of the underlying biological mechanisms.

“This approach is a building block for spotting early-stage Alzheimer’s,” he said. ”For high-accuracy Alzheimer’s prediction, genetic markers, other imaging markers, as well as test scores, lifestyle, nutrition, etc., will need to be considered jointly.”

MRI Homepage


You Must Be Logged In To Post A Comment

Anuncie
Aumente a Sua Perceção da Marca
Leilões + Vendas Privadas
Comece
O mais melhor preço
Comprar Equipamento/Peças
Encontre
O preço o mais baixo
Notícia diária
Leia
A notícia a mais atrasada
Diretório
Browse tudo
DOTmed Usuários
Ética no DOTmed
Veja o nosso
Programa das éticas
O ouro parte o programa do vendedor
Receba PH
Pedidos
Programa do negociante do serviço do ouro
Receba RFP/PS
Pedidos
Fornecedores de Healthcare
Veja tudo
Ferramentas de HCP
Trabalhos/Treinamento
Achado/suficiência
Um trabalho
Parts Hunter +EasyPay
Comece as peças
Citações
Certificado recentemente
Vista recentemente
Usuários certificados
Recentemente Rated
Vista recentemente
Usuários certificados
Central Rental
Equipamento do aluguel
Para menos
Vender Equipamentos/Peças
Comece
A maioria de dinheiro
Preste serviços de manutenção ao Forum dos técnicos
Ajuda do achado
E conselho
Simples RFP
Comece o equipamento
Citações
Mostra de comércio virtual
Serviço do achado
Para o equipamento
O acesso e o uso deste local são sujeitos aos termos e às condições do nosso OBSERVAÇÃO LEGAL & OBSERVAÇÃO DA PRIVACIDADE
Propriedade de e proprietário DOTmeda .com, Inc. Copyright ©2001-2017 DOTmed.com, Inc.
TODOS OS DIREITOS RESERVADOS